top of page
Neal Sondheimer.png
Neal Sondheimer
Medical Director at Synlogic

Neal Sondheimer, MD, PhD is a Medical Director at Synlogic responsible for the PKU and HCU programs. He also serves as the Medical Director for the PKU Clinic at SickKids Hospital Toronto and is a member of the faculty of Molecular Genetics and Pediatrics at the University of Toronto. 
Dr. Sondheimer received his medical degree and Ph.D. at The University of Chicago. His post-graduate medical education was at The Children’s Hospital of Philadelphia, and he specialized in Pediatrics, Clinical Genetics and Metabolic Genetics.

Recent Speaker List for 2023

  • March 19, 2023: Society for Inherited Metabolic Disorders (SIMD) 44th Annual Meeting Poster Presentation: SYNB1353, A Proposed Therapy for Homocystinuria, Lowers Plasma Methionine and Homocysteine in Healthy Volunteers Exposed to a Methionine Challenge. Presenting author: Dr. Neal Sondheimer, MD, PhD.

  • May 18, 2023: ANHI; Abbott Nutrition Health Institute. Presenting Synthetic Biotics for the Treatment of Phenylketonuria and Homocystinuria. Presented by Neal Sondheimer, MD, PhD.


Previous Years
2021. Genetics Past, Present and Future. - Children's Hospital of Philadelphia, Philadelphia, United States - Genetics Grand Rounds
2020. Mitochondrial Genetics of the MSSNG Cohort. Simons Foundation Meeting,
2020. Nuclear Genome-Wide Associations with Mitochondrial Heteroplasmy. UMDF - Bench to Bedside Series
2019. Mitochondrial Cytopathies - Treatment Options. Canadian College of Medical Genetics 2019
2019. Targeting Heteroplasmy in Mitochondrial Disease. Columbia University, United States
2019. Mitochondrial Genomes, Conflict and Phenotype. Invited Lecture Series - University of Bielefeld, Germany
2019. Mitonuclear Divergence and the Risk for Common Disease. Medical Grand Rounds – Hangzhou Children's Hospital, Hangzhou, China
2019. A Small Molecule Approach to Heteroplasmy Shifting. Garrod Association 2019 Meeting, Canada

bottom of page